Looking for affordable weekend trips from Tampa? We researched weekend flight pricing and availability from Tampa International Airport (TPA), and found the top 8 cheapest nonstop roundtrip weekend destinations. All routes offer direct flights to maximize weekend time.
Here's what we found. The top 8 cheapest weekend destinations from Tampa:
- Alcoa, TN (TYS)
- Charleston, SC (CHS)
- Atlanta, GA (ATL)
- Fort Worth, TX (DFW)
- Memphis, TN (MEM)
- Atlantic City, NJ (ACY)
- Asheville, NC (AVL)
- Charleston, WV (CRW)
1) Alcoa, TN (TYS) for $100
Alcoa, TN (TYS) is an occasional option from Tampa. Based on our data, Fri–Mon tends to be the cheaper option compared to Thu–Sun. The 8:08 pm Friday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Alcoa, TN
Alcoa offers gateway access to the Smoky Mountains—nearby hiking trails and the Tennessee River for kayaking provide adventure, while mountain town charm creates authentic Appalachian appeal. A rental car is necessary; the proximity to Great Smoky Mountains National Park creates outdoor access.
2) Charleston, SC (CHS) for $100
Charleston, SC (CHS) is one of the more consistent options from Tampa. Based on our data, Fri–Mon tends to be the cheaper option compared to Thu–Sun. The 8:29 pm Friday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Charleston, SC
Charleston offers historic Southern charm and culinary excellence—the historic district with antebellum architecture and waterfront parks provide character, while the restaurant scene punches above its weight. Walking dominates the historic core; rideshares extend reach. Check out our Weekend Guide to Charleston for even more travel ideas.
3) Atlanta, GA (ATL) for $100
Atlanta, GA (ATL) is one of the more consistent options from Tampa. Based on our data, Fri–Mon tends to be the cheaper option compared to Thu–Sun. The 7:55 pm Friday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Atlanta, GA
Atlanta offers Southern hospitality with metropolitan sophistication—Midtown delivers trendy restaurants and nightlife, while the historic neighborhoods like East Atlanta showcase street art and local character. Rideshares essential; walking works in specific neighborhoods. The food scene, brewery culture, and design community create genuine appeal. Check out our Weekend Guide to Atlanta for even more travel ideas.
4) Fort Worth, TX (DFW) for $100
Fort Worth, TX (DFW) is an occasional option from Tampa. Both Thu–Sun and Fri–Mon options are available at similar pricing. The 7:23 pm Friday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Fort Worth, TX
Fort Worth preserves authentic Western character—the Stockyards with nightly cattle drive and honky-tonks deliver genuine cowboy culture, while the vibrant downtown restaurants and galleries showcase revitalization. Rideshares work; walking handles specific areas. The heritage preservation combined with modern food scene creates unique appeal. Check out our Weekend Guide to Fort Worth for even more travel ideas.
5) Memphis, TN (MEM) for $100
Memphis, TN (MEM) is an occasional option from Tampa. Our research found only Thu–Sun flights available for this route. The 7:07 pm Thursday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Memphis, TN
Memphis owns American music history and riverside soul—Graceland pilgrimage and Beale Street deliver music immersion, while the creative community creates unexpected sophistication. Walking and rideshares handle downtown; the authentic food culture and music heritage create genuine appeal.
6) Atlantic City, NJ (ACY) for $100
Atlantic City, NJ (ACY) is an occasional option from Tampa. Our research found only Fri–Mon flights available for this route. The 6:55 pm Friday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Atlantic City, NJ
Atlantic City delivers boardwalk culture and beach energy—the iconic Boardwalk, casinos, and beaches provide entertainment and coastal access, while nearby nature preserves offer outdoor escapes. Walking dominates the boardwalk; the beach access and entertainment create seasonal appeal.
7) Asheville, NC (AVL) for $150
Asheville, NC (AVL) is an occasional option from Tampa. Our research found only Thu–Sun flights available for this route. The 8:51 pm Thursday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Asheville, NC
Asheville offers mountain culture and craft beer scene—Blue Ridge Parkway and nearby hiking provide mountain access, while downtown delivers galleries, breweries, and local restaurants. Walking and rideshares work; the mountain setting and creative community create genuine appeal. Check out our Weekend Guide to Asheville for even more travel ideas.
8) Charleston, WV (CRW) for $150
Charleston, WV (CRW) is a decent option from Tampa. Our research found only Thu–Sun flights available for this route. The 6:05 pm Thursday departure is the most common time we tracked. This route offers solid value and good availability.

Top things to do: Charleston, WV
Charleston delivers river culture and creative revival—the New River Gorge and downtown riverside offer outdoor and cultural appeal, while galleries and restaurants showcase revitalization. Walking and rideshares work; the outdoor recreation access creates adventure potential.
Ready to escape Tampa for a weekend?
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